Hypoglycemic α cycloalkylphenylmethyl, furanalkyl, and thiophenealkyl lactamimides

Article abstract of DOI:10.1021/jm00225a004

A series of α cycloalkylphenylmethyl lactamimides and a series of furan and thiophenealkyl lactamimides were prepared for biological evaluation as an extension of earlier findings of hypoglycemic activity in lactamimides. Several compounds produced pronouced hypoglycemia after oral administration to fasted, glucose primed rats.