Regioselective N-Methyl Carbon Lithiation of N-Boc-Methylalkylamines. Expedient Synthesis of Unsymmetrical Amines

DOI: 10.1016/S0040-4039(00)73113-3

Source and publish data:

Tetrahedron Letters p. 4067 - 4070 (1994)

Update date:2022-09-26

Topics:

Authors:

Snieckus, Victor

Roger-Evans, Mark

Beak, Peter

Lee, Won Koo

Yum, Eul Kyun

Freskos, John

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Article abstract of DOI:10.1016/S0040-4039(00)73113-3

The regioselective lithiation and functionalization at the N-methyl group of N-t-Boc-N-methylalkylamines 3 and 5 are shown with a variety of electrophiles

Full text of DOI:10.1016/S0040-4039(00)73113-3

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