Regioselective N-Methyl Carbon Lithiation of N-Boc-Methylalkylamines. Expedient Synthesis of Unsymmetrical Amines

DOI: 10.1016/S0040-4039(00)73113-3

Source and publish data:

Tetrahedron Letters p. 4067 - 4070 (1994)

Update date:2022-09-26

Topics:

Authors:

Snieckus, Victor

Roger-Evans, Mark

Beak, Peter

Lee, Won Koo

Yum, Eul Kyun

Freskos, John

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)73113-3

The regioselective lithiation and functionalization at the N-methyl group of N-t-Boc-N-methylalkylamines 3 and 5 are shown with a variety of electrophiles

Full text of DOI:10.1016/S0040-4039(00)73113-3

Products guided by the article

Product name:2-(isobutylamino)-1-phenylethanol

Cas No:55474-91-4

R&D Labs maybe for 55474-91-4

Suqian Ruixing Chemical Co., Ltd.

Contact:+86-527-80805666（总机）;84836008(销售)

Address:3 Jingsilu, Zone north, Hubin Xincheng Development Park, Suqian, China
Zhejiang Kangfeng Chemical Co.,LTD.

Contact:+86-579-86709687

Address:Xueshizhai Industrial Zone, Weishan Town,Dongyang City, Zhejiang Province ,China
Tianjin Pharmacn Medical Technology Co.,Ltd.

Contact:86-22-60122566ext.866(English),23359620

Address:Green Industrial Base, 6 Haitaifazhan Sixth Rd., Huayuan Industrial Area, Tianjin, 300384, China
Shanghai Run-Biotech Co., Ltd.

website:http://www.run-biotech.com

Contact:+86-21-31576854/57171705 / 57171706

Address:second floor, building 3, No.999, jiangyue Road, minghang District, Shanghai, China
ZHEJIANG JIANYE CHEMICAL CO.,LTD.

Contact:86-571-64149273,64149234

Address:No. 48, Fuxi Road, Meicheng Town

Relevant to this article

Synthesis of 3β-methyl ether of dehydroepiandrosterone by biotransformation of 3β-methyl ether of cholesterol with cells of mycobacteria Mycobacterium sp.

Doi:10.1007/s11172-019-2711-0
(2019)
A digalla[1.1]ferrocenophane and its coordination chemistry: Synthesis and structure of [{Fe(η⁵-C₅H₄)₂}₂ {GaMe}₂] and of the adducts [{Fe(η⁵-C₅H₄)₂}₂ {GaMe(D)}₂] (D = monodentate donor)

Doi:10.1021/om030115m
(2003)
Efficient Access to All-Carbon Quaternary and Tertiary α-Functionalized Homoallyl-type Aldehydes from Ketones

Doi:10.1002/anie.201706236
(2017)
FeCl₃·6H₂O supported on SiO₂ catalysed ring opening of epoxides with alcohols, acetic acid, water, chloride, bromide and nitrate ions

Doi:10.1055/s-1996-4416
(1996)
Alkyl group-tagged ruthenium indenylidene complexes: Synthesis, characterization and metathesis activity

Doi:10.1016/j.jorganchem.2015.04.054
(2015)
First enantioselective synthesis and absolute stereochemistry assignment of new monocyclic sesquiterpenes from Artemisia chamaemelifolia

Doi:10.1021/jo034424y
(2003)

Article Doi