Journal of Heterocyclic Chemistry p. 1397 - 1399 (1995)
Update date:2022-08-04
Topics:
Barton
Fabian
Lam
Sterbenz
This paper reports the large scale preparation of 7-ethoxy-3-hydroxy-6-methoxy-1-methyl-4-nitroisoquinoline (RWJ 19959, 2) from an available starting material, 4-ethoxy-3-methoxyphenylacetic acid (9). Previously 2 was prepared via a perchlorate salt which
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