Synthesis of complex intermediates for the study of a dehydratase from borrelidin biosynthesis

Article abstract of DOI:10.3762/bjoc.10.55

Herein, we describe the syntheses of a complex biosynthesis-intermediate analogue of the potent antitumor polyketide borrelidin and of reference molecules to determine the stereoselectivity of the dehydratase of borrelidin polyketide synthase module 3. Th