Taxus canadensis taxanes: Structures and stereochemistry

Article abstract of DOI:10.1139/v95-084

The structures and stereochemistry of 14 taxanes isolated from Taxus canadensis have been rigorously established by high-resolution NMR techniques and mass spectrometry. Taxus canadensis is the only yew that accumulates 9-dihydro-13-acetylbaccatin III (also called 7,9-deacetylbaccatin VI) as the most abundant taxane. Five 9-dihydrotaxanes derived from the Canadian yew are novel natural products not reported in the needles of other species of yew.