Aminotetralins as narcotic antagonists. 2. Synthesis and opiate-related activity of 1-phenyl-3-aminotetralins

DOI: 10.1021/jm00345a005

Source and publish data:

Journal of Medicinal Chemistry p. 216 - 220 (1982)

Update date:2022-08-04

Topics: Synthesis Narcotic Antagonists

Authors:

Fries Fries

Bertelli

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Article abstract of DOI:10.1021/jm00345a005

The synthesis and analgetic agonist and antagonist activities of several 3-[N-(cyclopropylmethyl)-N-methylamino]-1-phenyltetralins are reported. The design of these agents was based partially on the possibility of two aryl receptor binding sites on the op

Full text of DOI:10.1021/jm00345a005

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