
Bioorganic and Medicinal Chemistry Letters p. 2907 - 2911 (2003)
Update date:2022-08-04
Topics:
Gulledge, Brian M.
Aggen, James B.
Eng, Hugo
Sweimeh, Khuloud
Chamberlin, A. Richard
A series of greatly simplified microcystin analogues comprised only of Adda (the β-amino acid common to the microcystins, nodularins, and motuporin,) and a single additional amino acid residue was synthesized and screened for inhibition of the protein phosphatases 1 and 2A. Several of the analogues were shown to be mid-nanomolar inhibitors of the enzymes.
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(1980)Doi:10.1039/d0tc00408a
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