Journal of labelled compounds and radiopharmaceuticals p. 613 - 622 (2003)
Update date:2022-08-04
Topics:
Faragher, Robert J.
Motto, John M.
Kaminski, Maciej A.
Schwan, Adrian L.
A convenient synthesis of leflunomide and its primary pharmacologically active metabolite A77 1726, each labeled with four 13C atoms has been achieved. Starting from 13C4-ethyl acetoacetate, each step of the synthesis proc
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