Journal of the Chemical Society. Perkin transactions I p. 256 - 262 (1981)
Update date:2022-08-03
Topics: Formation Experimental Control Molecule Silicon
Fleming, Ian
Paterson, Ian
Pearce, Andrew
When γ-silyl-β-phenylthio-alcohols are treated with acid, the strategically placed silyl group encourages the rearrangement of the phenylthio-group, both from a secondary migration origin to a secondary migration terminus, and from a secondary migration origin to a tertiary migration terminus (4)->(6).Geraniol/nerol (12) and linalool (14) have been synthesised from a common intermediate (11) using this type of reaction.Phenylthio-migration from a tertiary migration origin (17)->(3) can be controlled to a limited extent by a suitably placed silyl group, but it is easier to achieve direct β-elimination of the silyl and phenylthio-groups (17)->(18).
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Doi:10.1016/S0040-4039(01)96115-5
(1973)Doi:10.1002/chem.200500152
(2005)Doi:10.1039/JR9600001103
()Doi:10.1016/S0031-9422(97)01135-7
(1998)Doi:10.1016/S0040-4020(01)80804-8
(1994)Doi:10.1248/yakushi1947.96.11_1352
(1976)
