Attempted inhibition of histidine decarboxylase with β aklyl analogues of histidine

DOI: 10.1021/jm00215a021

Source and publish data:

Journal of Medicinal Chemistry p. 721 - 723 (1977)

Update date:2022-07-29

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Authors:

Kelley Kelley

Miller Miller

McLean McLean

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Article abstract of DOI:10.1021/jm00215a021

The synthesis of β-methyl-(10b),β-ethyl-(10c), and β-n-hexylhistidine in five steps from 4-(N-triphenyl-methyl) imidazolecarboxaldehyde is described. Neither of the amino acids nor the methyl esters of 10b or 10c were inhibitors of the histidine decarboxylase from rat stomach.

Full text of DOI:10.1021/jm00215a021

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