Regioselective Syntheses of the Indolopyridine Alkaloids Nauclefine, Angustine, Dihydroangustine and Naucletine from a Common Intermediate

DOI: 10.1039/c39950001675

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1675 - 1676 (1995)

Update date:2022-08-03

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Authors:

Lavilla, Rodolfo

Gullon, Francisco

Bosch, Joan

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Article abstract of DOI:10.1039/c39950001675

A short, flexible route for the synthesis of the title indolopyridine alkaloids consisting of the cyclization of enamide 3, followed by introduction of the requisite pyridine substituent by Pd⁰-catalysed reactions from the resulting pentacyclic bromo intermediate 4 is reported.

Full text of DOI:10.1039/c39950001675

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