
Journal of Medicinal Chemistry p. 1201 - 1204 (1975)
Update date:2022-09-26
Topics:
Shulgin
Dyer
A homologous series of 4 alkyl 2,5 dimethoxyphenylisopropylamines (alkyl = H through n C5H11 and t C4H9) was synthesized and compared with mescaline as serotonin agonists in a sheep umbilical preparation. The three carbon homolog 6d was found to be the most potent of the straight chain series in accordance with its observed psychotomimetic effectiveness in man.
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