Quantification of lidocaine and several metabolites utilizing chemical ionization mass spectrometry and stable isotope labeling

Article abstract of DOI:10.1002/jps.2600660834

Quantification of the suspected metabolites of lidocaine in humans was carried out using the direct insertion probe and chemical-ionization mass spectrometry. Deuterated analogs of the metabolites of lidocaine were added to serial human plasma and urine s