SYNTHESES TOTALES ET ETUDES DE LIGNANES BIOLOGIQUEMENT ACTIFS-III; APPLICATION DE L'α-HYDROXYALKYLATION DE β-BENZYL γ-BUTYROLACTONES A LA CREATION DES SQUELETTES PHENYL TETRALINE ET BISBENZOCYCLOOCTADIENE. PREMIERE SYNTHESE DES PICROSTEGANES, SYNTHESE FOR

Article abstract of DOI:10.1016/S0040-4020(01)91503-0

Kinetically controlled intramolecular α-hydroxyalkylation of a suitable diphenyl aldehyde lactone gave a dibenzocyclooctenolactone having a cis lactone-ring junction, such as (+/-)-picrostegane and (+/-)-isopicrostegane.Subsequent transformations led to t