Tetrahedron Letters p. 3151 - 3154 (1981)
Update date:2022-08-03
Topics:
Secor, Henry V.
Chavdarian, Charles G.
Seeman, Jeffrey I.
2-Methylnicotine is a major product in the reaction nicotine with methyllithium and methyl radical, in addition to the previously reported 4- and 6-methylnicotines.The reaction of nicotine N-oxide with methylmagnesium bromide furnishes both 2- and 6-methylnicotine.
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(1957)
