Structures of two new cyclolanostanol xylosides, cimiacerosides A and B

Article abstract of DOI:10.3987/COM-98-8121

A new cyclolanostanolxyloside, cimiaceroside A, was isolated from Cimicifuga acerina (Miyagi) and Actaea asiatica, and another, cimiaceroside B, from C. simplex and C. acerina (Oki) respectively. The absolute stereo structures of cimiacerosides A and B were determined as 20(S),22(R),23(S),24(R)-16 β :23;22:25-diepoxy-3 β ,23,24-trihydroxy-9, 19-cyclolanost-7-ene-3-0- β-D-xylopyranoside and 20(S),22(R),23(S),24(R)-16 β :23;22:25-diepoxy-3 β ,23, 24-trihydroxy-9, 19-cyclolanostane-3-O- β-D-xylopyranoside on the basis of chemical and spectral data, and with the aid of a new version of Mosher's method.