Isoquinuclidine Mimics of β-D-Glucopyranosides: Differences and Similarities in the Mechanism of Action of some β-D-Glucosidases and a β-D-Mannosidase

Article abstract of DOI:10.1002/hlca.200390321

The D-gluco-isoquinuclidines 3 and 4 were prepared and tested as inhibitors of the β-glucosidases from Caldocellum saccharolyticum and from sweet almonds; the results are compared to the inhibition of snail β-mannosidase by the D-manno-isoquinuclidines 1