Thionylation of 5-alkyl-3H-furan-2-ones and their non-cyclic 4-oxoalkanoate ester analogs

Article abstract of DOI:10.1007/BF02251659

We have studied thionylation of 5-R-3H-furan-2-ones and 4-oxoalkanoates using phosphorus pentasulfide and the Lawesson reagent. It was found that the structure of the reaction products depended on the thionylating agent. Preparative methods have been developed for the synthesis of 5-R-5H- and 5-R-3H-thiophen-2-ones and 5-R-3H-furan-2-thiones. 1999 KluwerAcademic/Plenum.