Synthesis and Conformational Properties of 3,4-Difluoro- l -prolines

DOI: 10.1021/acs.joc.8b02920

Source and publish data:

Journal of Organic Chemistry p. 3100 - 3120 (2019)

Update date:2022-08-15

Topics:

Authors:

Hofman, Gert-Jan

Ottoy, Emile

Light, Mark E.

Kieffer, Bruno

Martins, Jose C.

Kuprov, Ilya

Sinnaeve, Davy

Linclau, Bruno

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Article abstract of DOI:10.1021/acs.joc.8b02920

Fluorinated proline derivatives have found diverse applications in areas ranging from medicinal chemistry over structural biochemistry to organocatalysis. Depending on the stereochemistry of monofluorination at the proline 3- or 4-position, different effe

Full text of DOI:10.1021/acs.joc.8b02920

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