Total syntheses of lamellarin D and H. The first synthesis of lamellarin-class marine alkaloids

DOI: 10.1016/S0040-4020(97)00287-1

Source and publish data:

Tetrahedron p. 5951 - 5962 (1997)

Update date:2022-08-05

Topics:

Authors:

Ishibashi, Fumito

Miyazaki, Yuka

Iwao, Masatomo

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Article abstract of DOI:10.1016/S0040-4020(97)00287-1

Total syntheses of marine polyaromatic alkaloids, lamellarin D (1) and H (2), are described. The pentacyclic lamellarin ring system was constructed by N-ylide mediated pyrrole ring formation and subsequent lactonization of 4 obtained by an assembly of known benzylisoquinoline 5, benzoate 6 and ethyl bromoacetate.

Full text of DOI:10.1016/S0040-4020(97)00287-1

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