
Tetrahedron p. 5951 - 5962 (1997)
Update date:2022-08-05
Topics:
Ishibashi, Fumito
Miyazaki, Yuka
Iwao, Masatomo
Total syntheses of marine polyaromatic alkaloids, lamellarin D (1) and H (2), are described. The pentacyclic lamellarin ring system was constructed by N-ylide mediated pyrrole ring formation and subsequent lactonization of 4 obtained by an assembly of known benzylisoquinoline 5, benzoate 6 and ethyl bromoacetate.
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