Bioorganic and Medicinal Chemistry Letters p. 409 - 412 (2004)
Update date:2022-08-06
Topics:
Bingham, Alistair H.
Davenport, Richard J.
Gowers, Lewis
Knight, Roland L.
Lowe, Christopher
Owen, David A.
Parry, David M.
Pitt, Will R.
A novel series of aminopyrimidine IKK2 inhibitors have been developed which show excellent in vitro inhibition of this enzyme and good selectivity over the IKK1 isoform. The relative potency and selectivity of these compounds has been rationalized using QSAR and structure-based modelling.
View MoreRudong Zhenfeng Yiyang Chemical Co., Ltd.
Contact:0513-84573047
Address:South Fengli Town, Rudong County, Jiangsu Province, China
Hangzhou Yanshan Chemical Co.,Ltd.
Contact:86-571- 87698076
Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
Hebei Think-Do Environment Co., Ltd
website:http://www.thinkdo-environment.com
Contact:0311-86510809-
Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Shanghai Mio Chemical Co., Ltd
Contact:0086 21- 64401188-622
Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China
Contact:13813902930 025-52714267
Address:20 Fengji Road, Yuhua Economic Development Zone, Nanjing, Jiangsu, P. R. China
Doi:10.1021/jf60220a006
(1978)Doi:10.1002/ejoc.201300506
(2013)Doi:10.1016/j.poly.2019.114217
(2020)Doi:10.1021/jo501014e
(2014)Doi:10.1016/j.bmcl.2010.09.028
(2010)Doi:10.1021/jm00167a013
(1990)
