ATTOGRAM-LEVEL DETECTION AND RELATIVE RESPONSE OF STRONG ELECTROPHORES BY GAS CHROMATOGRAPHY WITH ELECTRON CAPTURE DETECTION.

Article abstract of DOI:10.1021/ac00240a029

The responses as peak areas of some divergent compounds, most of which are strong electron absorbers, are measured by gas chromatography with electron capture detection (GC-ECD). The most sensitive compounds are derivatized lodothyronines, which are essentially 20-fold more sensitive than lindane. N,N-Dipentafluorobenzoylpentafluoroaniline, a somewhat less sensitive but more volatile substance, was selected for determination of a detection limit. The value was 90 ag(1. 6 multiplied by 10** minus **1**9 mol), largely due to an anomalous increase in its response at the trace level. This increases the reported sensitivity of GC-ECD by 100-fold.