Journal of Medicinal Chemistry p. 883 - 887 (1993)
Update date:2022-07-30
Topics:
Liu
Wnuk
Yuan
Robins
Borchardt
Adenosine-5'-carboxaldehyde (3) and its 4'-epimer (4) were synthesized and shown to be potent type I mechanism-based inhibitors of recombinant rat liver AdoHcy hydrolase with k2/K1 values of 16.7 x 10-3 and 5.5 x 10-3
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