REACTION OF β-AMINO-α,β-UNSATURATED ESTERS AND AMIDES WITH ARYL DIAZONIUM SALTS. SYNTHESIS OF CINNOLINE DERIVATIVES

Article abstract of DOI:10.1016/S0040-4020(01)98868-4

Conjugated esters and amides react with aryldiazonium salts at room temperature (MeCN) to form the corresponding iminium hydrazone derivatives, which can be thermally cyclized to cinnoline-3-esters and cinnoline-3-amides.In general the intermediate iminiu