Tetrahedron p. 4547 - 4554 (1991)
Update date:2022-09-26
Topics:
Gustafson, Kirk R.
Munro, Murray H. G.
Blunt, John W.
Cardellina, John H.
McMahon, James B.
et al.
Extracts of the tropical rainforest trees Homalanthus acuminatus and Chrysobalanus icaco were active in the NCI AIDS-antiviral screen.Diterpenes 1-4 were found in H. acuminatus, while two (6, 7) were found in C. icaco.Compounds 1 and 6 were active in the anti-HIV screen; 1, 3 and 4 were previously unknown.
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