Tricyclics with analgesic and antidepressant activity: I. [[(Alkylamino)ethyl]thio]dibenzo[b,f]oxepins and 10,11-dihydro derivatives

DOI: 10.1021/jm00179a005

Source and publish data:

Journal of Medicinal Chemistry p. 494 - 501 (1980)

Update date:2022-07-29

Topics:

Authors:

Ong Ong

Profitt Profitt

Anderson

Spaulding

Wilker Wilker

Geyer IIIrd

Kruse Kruse

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Article abstract of DOI:10.1021/jm00179a005

A series of [[(alkylamino)ethyl]thio]dibenz[b,f]oxepins and their 10,11-dihydro derivatives was synthesized and subjected to broad analgesic/CNS screening. Several analogues of both types, carrying small N-substituents and frequently a nuclear fluorine fu

Full text of DOI:10.1021/jm00179a005

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