Journal of Medicinal Chemistry p. 1503 - 1505 (1982)
Update date:2022-07-30
Topics:
Lund, Mary Q.
Kier, Lemont B.
Glennon, Richard A.
Egle, John L.
Several mesoionic 3-(substituted-aryl)-ψ-oxatriazole derivatives were prepared and evaluated as potential antihypertensive agents. 3-(4-Methylphenyl)-ψ-oxatriazole was found to produce a significant hypotensive effect in rats, which was characterized by a
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