Preliminary Studies of Mesoionic 3-(Substituted-aryl)-ψ-oxatriazoles as Potential Antihypertensive Agents

DOI: 10.1021/jm00354a023

Source and publish data:

Journal of Medicinal Chemistry p. 1503 - 1505 (1982)

Update date:2022-07-30

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Authors:

Lund, Mary Q.

Kier, Lemont B.

Glennon, Richard A.

Egle, John L.

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Article abstract of DOI:10.1021/jm00354a023

Several mesoionic 3-(substituted-aryl)-ψ-oxatriazole derivatives were prepared and evaluated as potential antihypertensive agents. 3-(4-Methylphenyl)-ψ-oxatriazole was found to produce a significant hypotensive effect in rats, which was characterized by a

Full text of DOI:10.1021/jm00354a023

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