NITROGEN BRIDGEHEAD COMPOUNDS PART 16. FACILE TOTAL SYNTHESIS OF 7,8-DIHYDRO-13H-INDOLOPYRIDO-QUINAZOLIN-5-ONE (RUTECARPINE).

DOI: 10.1016/S0040-4039(01)92365-2

Source and publish data:

Tetrahedron Letters p. 4861 - 4862 (1981)

Update date:2022-07-29

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Authors:

Koekoesi, Jozsef

Hermecz, Istvan

Szasz, Gyoergy

Meszaros, Zoltan

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Article abstract of DOI:10.1016/S0040-4039(01)92365-2

Rutecarpine 1 has been synthetised from hydrazone 2 in high yield by Fischer indole synthesis.Hydrazone 2 has been prepared from 3 with benzenediazonium chloride or 5 with phenylhydrazine. 2 Shows a solvent dependent E-Z isomerism.

Full text of DOI:10.1016/S0040-4039(01)92365-2

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