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Synthesis of the trans-3,4-Dihydrodiol Metabolites of the Steroid-Related Carcinogen 15,16-Dihydrocyclopentaphenanthren-17-one and Its 11-Methyl Derivative

DOI: 10.1021/jo00054a018

Source and publish data:

Journal of Organic Chemistry p. 361 - 365 (1993)

Update date:2022-07-30

Topics:

Authors:

Harvey, Ronald G.

Young, Robert J.

Cortez, Cecilia

Lee, Hongmee

Luna, Ernestina

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Article abstract of DOI:10.1021/jo00054a018

Cyclopentaphenanthrenes are a class of carcinogenic polycyclic aromatic hydrocarbons that are structurally related to steroids.Optimum tumorigenic activity is associated with a methyl group in the 11-position and a keto group in the 17-position.Synthes

Full text of DOI:10.1021/jo00054a018

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Product name:3,4,15,16-tetrahydro-3,4-dihydroxy-11-methyl-17H-cyclopenta(a)phenanthren-17-one

Cas No:72007-69-3

72007-69-3

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