THE ACETATE OF (Z)-4-CHLORO-2-METHYL-2-BUTEN-1-OL. STEREOSELECTIVE WITTIG SYNTHESIS OF A NEW HEMITERPENOID SYNTHON

Article abstract of DOI:10.1016/S0040-4039(00)87305-0

a synthetic method for the preparation of the acetate of (Z)-4-chloro-2-methyl-2-buten-1-ol, a precursor of the (Z)-hydroxy prenyl synthon is described.The use of such synthon in the preparation of a metabolite of aprenyl-containing substance is also illustrated.