Journal of Organic Chemistry p. 1246 - 1249 (1980)
Update date:2022-08-05
Topics:
Nelson, John H.
Howells, Peter N.
DeLullo, George C.
Landen, George L.
Henry, Ronald A.
Bis(2,4-pentanedionato)nickel(II) is found to be a mild, efficient, and simple to use catalyst for the Michael additions of β-dicarbonyls.Yields are higher than with traditional strongly basic catalysts, unwanted side reactions are reduced, and workup procedures are greatly simplified.The reactions appear to be quite general as β-diketones, β-keto esters, β-keto amides, and β-diesters are all found to react.A rational mechanism which suggests further research is presented.
View MoreContact:+44 (0)161 367 9441
Address:
Contact:+86-21-6856-1349 523-87676172
Address:No16 . BinJiang Road . Taixing Economy Developing Area .JiangSu Province . China
Contact:+ 86 512 52491118
Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Suzhou Chiral Pharmaceuticals Co., Ltd.
Contact:86-0512-63197058
Address:Building A, No. 2358, Chang'an Road, Wujiang Science Park
Beijing Cooperate Pharmaceutical Co.,Ltd
website:http://www.cooperate-pharm.com/
Contact:86-01060279497
Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base
Doi:10.1002/hlca.19940770723
(1994)Doi:10.1021/ja00802a029
(1973)Doi:10.1016/S0040-4020(01)93740-8
(1979)Doi:10.1016/j.bmcl.2004.03.065
(2004)Doi:10.1021/ol201140q
(2011)Doi:10.1021/ja00500a048
(1979)
