Regiospecific Nucleophilic Aromatic Substitution: Conjugate Addition of Active Methylene Compounds to Quinone Monoacetals and Aromatization of the Adducts

Article abstract of DOI:10.1021/jo01295a010

Diethyl malonate adds to a variety of quinone monoacetals in a Michael reaction; acid-catalyzed loss of methanol and enolization converts the adducts to hydroquinone monoethers substituted ortho to the alkoxy substituent.The same sequence applied to ethyl