2-phenylthio-3,3,3-trifluoropropene, its sulfoxide and sulfone : Synthesis and reactivity in 1,3-dipolar cycloadditions

Article abstract of DOI:10.1016/0040-4020(96)00082-8

Derivatives of 3,3,3-trifluoropropene 1 : α-sulfide 2, sulfoxide 3, sulfone 4 and bromide 6 are useful trifluoromethylated synthons. On reaction with diazo compounds, these derivatives can afford trifluoromethyl substituted pyrazolines, pyrazoles, cyclopropanes or allylsulfones in fair to excellent yields. 1,3-Dipolar cycloaddition of trifluoropropene derivatives 2-4 with N-benzyl-azomethine ylide provides disubstituted 3-trifluoromethyl-pyrrolidines.