SYNTHESIS OF A CHIRAL 1,1,3-TRIMETHYLCYCLOHEXANE DERIVATIVE FROM d-CAMPHOR: A POTENT KEY BUILDING BLOCK FOR ENT-TAXANE-TYPE DITERPENOIDS

DOI: 10.1246/cl.1980.1001

Source and publish data:

Chemistry Letters p. 1001 - 1004 (1980)

Update date:2022-09-26

Topics:

Authors:

Kitagawa, Isao

Shibuya, Hirotaka

Fujioka, Hiromichi

Kajiwara, Akiharu

Tsujii, Shinji

Yamamoto, Yoshio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1980.1001

A chiral 1,1,3-trimethylcyclohexane derivative (12), which is a potent key building block for synthesis of ent-taxane-type diterpenoids, has been prepared from d-camphor (2) through a conversion pathway which involves a novel ring enlargement reaction of a 1,1,2-trimethylcyclopentane derivative (3).

Full text of DOI:10.1246/cl.1980.1001

Products guided by the article

Product name:Acetic acid (1S,4S)-4-bromomethyl-2,2-dimethyl-3-methylene-cyclohexylmethyl ester

Cas No:73616-73-6

R&D Labs maybe for 73616-73-6

zhuzhou zhongle chemical co. ltd.

Contact:+86-0731 28228409

Address:Zhuzhou, Hunan, China
Chengdu Green Young Biopharmaceutical INC

Contact:+86-28-85337952

Address:1-B-26,Tianhe Industry Park, No.1480 of Tianfu Road,Chengdu,P.R.China,610000
QINGDAO DEVELOP chemistry Co.,Limited

Contact:+86-532-85807910

Address:98#Nanjing Road, Qingdao, China 266071
Airsea(Taizhou) Pharmaceutical Limited(expird)

Contact:+86-576-88057622

Address:Dubei, Duqiao, Linhai, Taizhou, Zhejiang, China Zip: 317016
Phantom-pharma

Contact:

Address:

Relevant to this article

Platinum(II) chloride catalyzed cycloisomerizations of 1,5-enynes

Doi:10.1055/s-2007-983736
(2007)
A mild and efficient method for the deformylation of 5-formyl uracils and synthesis of 4,4￠-methylidenebis(1-phenyl-3-methyl-5-pyrazolone)

Doi:10.1055/s-0029-1217536
(2009)
N-Propynyl analogs of β-phenylethylidenehydrazines: Synthesis and evaluation of effects on glycine, GABA, and monoamine oxidase

Doi:10.1016/j.bmc.2008.07.027
(2008)
Doi:10.1021/ja01098a508
(1953)
Synthesis of hydroxylated PCB metabolites with the Suzuki-coupling

Doi:10.1016/S0045-6535(01)00052-2
(2001)
Doi:10.1016/S0040-4039(01)86764-2
(1979)

Article Doi