Potential prophylactic antitumor activity of retinylidene 1,3-diketones

DOI: 10.1021/jm00181a019

Source and publish data:

Journal of Medicinal Chemistry p. 805 - 809 (1980)

Update date:2022-07-30

Topics:

Authors:

Acton Acton

Brossi Brossi

Newton Newton

Sporn Sporn

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Article abstract of DOI:10.1021/jm00181a019

Treatment of all-trans-retinal with a series of 1,3-diketones using Knoevenagel conditions gave the expected condensation products. These retinylidene 1,3-diketones were characterized and their biological activities in the hamster tracheal organ culture t

Full text of DOI:10.1021/jm00181a019

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Product name:2-[(2Z,4Z,6Z,8Z)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ylidene]cyclooctane-1,3-dione

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