Journal of Medicinal Chemistry p. 627 - 631 (1980)
Update date:2022-08-05
Topics:
Newman
Lin
Sartorelli
A number of hydroquinone dialdehydes and structually related compounds were synthesized and tested for antineoplastic efficacy against transplanted murine tumors. 3,6-Dihydroxy-4,5-dimethylphthalaldehyde, 3,6-dihydroxy-4,5-dipropylphthalaldehyde, and 3,6-dihydroxy-4,5-dimethylphthalaldehyde hemialdal tetraacetate significantly prolonged the survival time of mice bearing either Sarcoma 180, Ehrlich carcinoma, or adenocarcinoma 755 ascites tumors. In addition, these agents were cytotoxic to Sarcoma 180 cells in culture at concentrations in the range of 25-30 μM.
View MoreJinan Yijialian Economic and Trade Development Co., Ltd.
Contact:+86 0531-66729596
Address:jinan
Taizhou Chemedir Biopharm-tech Co., Ltd
Contact:+86 523 86200218
Address:G09, No. 1 Avenue China Medical City, Taizhou,Jiangsu, China
Contact:+86-(0)21-3770 9035
Address:Room 301, Building 2, Meijiabang Road 1508, Shanghai China
shanghai jiuling chemical co.,ltd.
Contact:+86-21-50387295
Address:Zaozhuang Road, Pudong, Shanghai City. China
Contact:+8613400661290
Address:No 908,Kangwan Rd, Liuyang Economic
Doi:10.1007/BF00579419
(1982)Doi:10.1016/S0008-6215(97)10003-9
(1997)Doi:10.1016/S0040-4039(01)95546-7
(1979)Doi:10.1016/j.bmcl.2004.04.064
(2004)Doi:10.1002/anie.201204083
(2012)Doi:10.1248/cpb.24.349
(1976)
