Journal of Medicinal Chemistry p. 750 - 754 (1980)
Update date:2022-08-02
Topics: Bioassay Chemical Synthesis
Cannon
Koble
Long
Verimer
The title compounds were designed to provide semirigid congeners of m-tyramine in which the ring position ortho to the phenolic OH is blocked to metabolic hydroxylation. A sequence leading to a key synthetic intermediate, 5-methoxy-6-methyl-2-tetralone, h
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