Chemistry of Heterocyclic Compounds p. 189 - 194 (1980)
Update date:2022-07-29
Topics:
Pevzner, M. S.
Ivanov, P. A.
Gladkova, N. V.
Sushchenko, O.N.
Tverdokhlebov, V. P.
Myasnikova, Z. S.
1-Hydroxymethyl derivatives of tetrazoles were obtained by the reaction of 1,2,4-triazole and 3-nitro-5-substituted triazoles with formaldehyde in water.The hydroxy groups were replaced by chlorine, and the hydroxymethyltriazoles were acetylated and tosylated.The chloro and tosyl groups are readily replaced by iodine by the action of potassium and ammonium iodide in acetone.
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Doi:10.1021/ja01638a037
(1954)Doi:10.1002/anie.200802472
(2008)Doi:10.1016/0040-4020(80)80022-6
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(1980)Doi:10.1021/ja00541a021
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(1982)
