A Convenient One-Pot Synthesis of 4-Substituted 3,5-Bis(alkoxycarbonyl)-4,5-dihydroisoxazole 2-Oxides from Aldehydes and Nitroacetic Esters in a Solid-Liquid Reaction System and Subsequent Deoxygenation

Article abstract of DOI:10.1055/s-1988-27639

4-Substituted 3,5-bis(alkoxycarbonyl)-4,5-dihydroisoxazole 2-oxides are obtained from nitroacetic esters and imines which are prepared from aldehydes and isopropylamine in the presence of molecular sieves.Reduction of the N-oxides with trimethyl phosphite