Journal of Medicinal Chemistry p. 2976 - 2981 (1990)
Update date:2022-08-04
Topics:
Engel, Juergen
Fleischhauer, Ilona
Jakovlev, Vladimir
Kleemann, Axel
Kutscher, Bernhard
et al.
In the course of studies on tranquilizers, new non-benzodiazepine-like compounds were synthesized.These are 1-(3,4,5-trimethoxyphenoxy)-3-<4-(2-methoxyphenyl)piperazinyl>propan-2-ol (INN: enciprazine) and derivatives thereof which were screened pharmacologically in order to evaluate their central nervous system activity.Compounds with marked antiaggressive and anxiolytic properties but without dependence potential could be detected.Enciprazine was selected for clinical investigations.
View MoreKunshan Yalong Trading Co,.Ltd
Contact:86-512-57621185
Address:805-807 Room Hongqiao Mansion ,1088 West Qianjin Road, Kunshan, Jiangsu，China
Jurong Huaheng Natural Biological Products Factory
website:http://www.risebiochem.com
Contact:+86-13921007726
Address:Chuncheng town,Jurong city,Jiangsu province,China
Wuxi Zuping Food Science And Technology Co.,LTD.
Contact:+86-510-87210822
Address:Guanlin town
Zibo Ocean International Trade Co.,Ltd(expird)
Contact:+86 533 5160706
Address:1117, Hongtai Bld., Songling rd, Zichuan,Zibo,Shandong,China
HANGZHOU YUNUO CHEMICAL CO.,LTD
website:http://www.yunuochem.com
Contact:0571-83715115
Address:hangzhou
Doi:10.1021/ja01372a045
(1930)Doi:10.1071/CH03238
(2004)Doi:10.1021/jo01312a008
(1980)Doi:10.1002/hlca.660280147
(1945)Doi:10.1016/S0022-328X(00)81230-9
(1980)Doi:10.1016/j.ejmech.2019.111923
(2020)
