
Journal of Medicinal Chemistry p. 1445 - 1448 (1980)
Update date:2022-08-05
Topics:
Fogt
Scozzie
Heilman
Powers
In an attempt to enhance the antihypertensive activity of 4-acetyl-2-(2-hydroxyethyl)-5,6-bis(4-chlorophenyl)-2H-pyridazin-3-one, (1), a series of lipophilic and hydrophilic esters was synthesized. These derivatives possessed increased lipid and aqueous s
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Doi:10.1021/jo01314a002
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(1981)