Journal of Medicinal Chemistry p. 251 - 256 (1981)
Update date:2022-07-30
Topics: Medicinal chemistry Biological Activity Colchicine Mice
Quinn, Frank R.
Beisler, John A.
A quantitative structure-activity relationship (QSAR) was derived for colchicine and 14 analogues acting against P388 lymphocytic leukemia in mice.Twelve additional compounds were synthesized to reinforce and confirm the correlation.The final correlation
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