Journal of Organic Chemistry p. 1413 - 1423 (1981)
Update date:2022-08-04
Topics:
Hagmann, William K.
Basha, Fatima Z.
Hashimoto, Mitsunori
Frye, Bruce R.
Kojo, Shosuke
Hecht, Sidney M.
Synthetic approaches to 2-substituted pyrimidines have been studied in an effort to facilitate the preparation of the pyrimidine moiety of bleomycin (2).Ethyl 2,5-dimethyl-4-oxopyrimidine-6-carboxylate (4) has been utilized as starting material; its conve
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(2013)Doi:10.1021/jo00322a021
(1981)
