Tetrahedron Letters p. 3295 - 3298 (1980)
Update date:2022-08-04
Topics:
Sharma
Gupta
Bindra
Sunita
Monocyclic β-lactams (V & XI) carrying a carboxy function have been used to annelate the Schiff bases (II & X) using POCl3 in the presence of triethylamine to obtain the di-β-lactams (VI & XII). Alternately, (VI) could also be prepared by annelation of the Schiff base (IX) derived from the α-amino-β-lactam (VIII), with phenoxyacetyl chloride.
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(2021)
