1,4:3,6-DIANHYDRO-2,5-DIDEOXY-2,5-BIS(DIPHENYLPHOSPHINO)-L-IDITOL. A NEW CHIRAL LIGAND FOR ASYMMETRIC HYDROGENATION WITH RHODIUM COMPLEXES AS CATALYSTS

Article abstract of DOI:10.1016/0022-328X(83)80123-5

A new chiral 1,4-diphosphine, 1,4:3,6-dianhydro-2,5-dideoxy-2,5-bis(diphenylphosphino)-L-iditol, has been prepared from D-mannitol.Rhodium complexes of this ligand are asymmetric homogeneous hydrogenation catalysts for dehydroamino acids, giving (S)-amino acids in 21-58percent optical yields.