STRUCTURE AND CHEMICAL SYNTHESIS OF ME-IQ, A POTENT MUTAGEN ISOLATED FROM BROILED FISH

DOI: 10.1246/cl.1980.1391

Source and publish data:

Chemistry Letters p. 1391 - 1394 (1980)

Update date:2022-07-30

Topics:

Authors:

Kasai, Hiroshi

Yamaizumi, Ziro

Wakabayashi, Keiji

Nagao, Minako

Sugimura, Takashi

et al. et al.

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Article abstract of DOI:10.1246/cl.1980.1391

Structure of a mutagenic compound (Me-IQ) isolated from broiled fish was determined to be 2-amino-3,4-dimethylimidazo<4,5-f>quinoline based on the mass-, UV- and 1HNMR-spectra and chemical synthesis.Me-IQ showed strong mutagenic activity towards Salmonella typhimurium TA98 in the presence of S-9 mix.

Full text of DOI:10.1246/cl.1980.1391

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