Journal of the Chemical Society. Perkin transactions I p. 465 - 470 (1981)
Update date:2022-08-05
Topics:
Broom, Nigel J. P.
Sammes, Peter G.
The lithium salts, derived from position 3 of phthalides by treatment with hindered bases, participate in Michael addition reactions with a variety of conjugated olefins.For singly activated olefins the conjugate anion reacts intramolecularly with the lactone group to produce 4-hydroxytetralones in moderate to good yield.Dehydration of these hydroxytetralones, by brief treatment with acid, produces the corresponding α-naphthol.Substituted phthalides react similarly making the method a general one for the production of substituted α-naphthols.
View MoreNingbo Distant Chemicals Co.,Ltd
Contact:86-574-27862490,27862438
Address:5F-3,#54 DaShaNi street,Ningbo,CHINA
Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd
Contact:86-27-52341789
Address:Room 1518 B suite, optical valley time square, No 111 Guanshan Road, Hongshan District,Wuhan,Hubei Province,China.
Jinan Aery Pharmaceutical Co,.Ltd
Contact:+8653181263406
Address:1-1916,Building1 Fenghuang SOHO,Fenghuang Road,High-tech Zone,Jinan,Shandong
Contact:+8618766299236
Address:ROOM808, BUILDING2,NO.230 SHEN ZHEN ROAD, LAOSHAN DISTRICT
Huzhou City Linghu Xinwang Chemical Co.,Ltd.
Contact:86-572-3948695/3945236
Address:huzhou
Doi:10.1021/acs.orglett.1c00992
(2021)Doi:10.1016/0040-4020(79)85048-6
(1979)Doi:10.1021/ja037076q
(2003)Doi:10.1016/0040-4020(77)80226-3
(1977)Doi:10.1016/S0040-4020(01)87978-3
(1993)Doi:10.1023/A:1010495500525
(2000)
