Synthesis and Preliminary Pharmacological Evaluation of Asymmetric Chloroquine Analogues

DOI: 10.1021/jm00138a014

Source and publish data:

Journal of Medicinal Chemistry p. 712 - 717 (1981)

Update date:2022-08-04

Topics:

Authors:

Witiak, Donald T.

Grattan, David A.

Heaslip, Richard J.

Rahwan, Ralf G.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00138a014

Asymmetric chloroquine analogues (1-4) were prepared of known absolute configuration in order to assess stereochemical influences on selected biological activities.Since chloroquine has been shown to possess spasmolytic properties, analogues 1-4 were test

Full text of DOI:10.1021/jm00138a014

Products guided by the article

Product name:2-[(7-chloroquinolin-4-yl)amino]-5-(diethylamino)pentan-1-ol

Cas No:77529-96-5

R&D Labs maybe for 77529-96-5

Shandong Xiangde Biotechnology Co., Ltd

Contact:+86 -15066639877

Address:Sanba street
Liaoyang hengye Chemical Co., Ltd.

Contact:86-419-5850866

Address:North Old Xiaoxiao Road,Yantai District, Dengta, Liaoyang, Liaoning, China
Zhuhai Rundu Pharmaceutical co.,Ltd

Contact:+86-756-7630755

Address:No.6,North Airport Road,Sanzao Town,Jinwan District
ZHEJIANG CHEMICAL INDUSTRY INSTITUTE TECHNOLOGY CO.,LTD(expird)

Contact:86-575-82730298

Address:shangyu
Shaanxi HuaTai Bio-fine chemical company Ltd

Contact:86-029-87862197

Address:No. 5, 3rd Floor, 29 Yanta North Road, Beilin Dist.

Relevant to this article

Synthesis of 7-bromo-3-(α-D-mannopyranosyloxy)-2-naphth-o-anisidide, a D-mannosyl derivative of naphthol AS-BI

Doi:10.1016/S0008-6215(00)85262-3
(1981)
Doi:10.1007/BF02539913
(1958)
Water-Sculpting of a Heterogeneous Nanoparticle Precatalyst for Mizoroki-Heck Couplings under Aqueous Micellar Catalysis Conditions

Doi:10.1021/jacs.0c11484
(2021)
The regioselective [2 + 2] photocycloaddition reaction of 2-(3,4-dimethoxystyryl)quinoxaline in solution

Doi:10.1039/c9pp00028c
(2019)
Asymmetric oxidation of sulfides with H₂O₂ catalyzed by (salen)Mn(III) complexes

Doi:10.1016/S0040-4039(00)60849-3
(1992)
Fluorinations of uracil and 3-O-acetyldigitoxigenin

Doi:10.1002/cber.19811140334
(1981)

Article Doi