2-(Arylmethyl)arylacetic Acids as Potential Antiinflammatory Agents

DOI: 10.1021/jm00140a016

Source and publish data:

Journal of Medicinal Chemistry p. 998 - 1000 (1981)

Update date:2022-08-02

Topics: Chemical Synthesis Anti-Inflammatory Structure-Activity Relationship Experimental Design In vitro assay Inflammatory mediators In vivo study

Authors:

Brancaccio, Giovanni

Larizza, Angelo

Lettieri, Guglielmo

Monforte, Pietro

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Article abstract of DOI:10.1021/jm00140a016

The title compounds 2 have been synthesized and tested for antiinflammatory activity.The synthetic method, consisting of the chemical sequence 3-aryl-1H-indenes (4) <*> 2-(aroyl)arylacetic acids (5) <*> 2, appears to be of value because of its simplicity

Full text of DOI:10.1021/jm00140a016

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