Synthesis of 3-Aryl-3-pyridylallylamines Related to Zimelidine via Palladium-Catalyzed Amination

DOI: 10.1021/jo00330a019

Source and publish data:

Journal of Organic Chemistry p. 3479 - 3483 (1981)

Update date:2022-08-04

Topics:

Authors:

Baeckvall, Jan-E.

Nordberg, Ruth E.

Nystroem, Jan-E.

Hoegberg, Thomas

Ulff, Bengt

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00330a019

Reaction of aryl pyridyl ketones 1 with vinylmagnesium bromide followed by acetylation of the products 2 with acetic anhydride/Et3N and with 4-(dimethylamino)pyridine (DMAP) as a catalyst gave acetates 3 in high yields.Treatment of acetates 3 with dimethylamine in the presence of a palladium catalyst produced a mixture of E and Z isomers of 3-aryl-3-pyridylallylamines 4.

Full text of DOI:10.1021/jo00330a019

Products guided by the article

Product name:Acetic acid 1-phenyl-1-pyridin-3-yl-allyl ester

Cas No:77744-15-1

R&D Labs maybe for 77744-15-1

jiangsu haian chemical co.,ltd.

Contact:86-513-15851283853

Address:No.99,Changjiang West Road,Haian County,Jiangsu Province,China
Shanghai Forever Biotech Co., Ltd.

Contact:+86-21-69734790

Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.
SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

website:http://www.zhongbangst.com

Contact:86-830-2585019

Address:sichuan,china
Sichuan JieYao Co., Ltd.

Contact:+86-838-5655598

Address:Guanghan Nanfeng Industrial Zone
Huayang chemical Co., LTD

Contact:+86-18653358619

Address:zibo

Relevant to this article

Accurate prediction of glucuronidation of structurally diverse phenolics by human UGT1A9 using combined experimental and in silico approaches

Doi:10.1007/s11095-012-0666-z
(2012)
Reactivity of Carbon Acids toward 4,6-Dinitrobenzofuroxan. Studies of Keto-Enol Equilibria and Diastereoisomerism in Carbon-Bonded Anionic ? Complexes

Doi:10.1021/jo00330a033
(1981)
Aqueous Glycosylation of Unprotected Sucrose Employing Glycosyl Fluorides in the Presence of Calcium Ion and Trimethylamine

Doi:10.1021/jacs.5b13384
(2016)
VERSATILITE DE REACTIVITE DE L'ACETYLENE DICARBALDEHYDE ET DES ALDEHYDES α-ACETYLENIQUES A L'EGARD DES DIENES CONJUGUES CYCLIQUES ET HETEROCYCLIQUES EN MILIEU ACIDE

Doi:10.1016/S0040-4020(01)87436-6
(1986)
Reactions of co-ordinated ligands. Part 24. The reaction of bis-(but-2-yne)carbonyl(η-cyclopentadienyl or η⁵-indenyl)molybdenum tetrafluoroborate with acetonitrile and phosphines; crystal structures of ...

Doi:10.1039/DT9810000873
(1981)
Doi:10.1021/ja00402a040
(1981)

Article Doi